BDBM521609 US11149054, Compound 4657

SMILES COC[C@H]1CC[C@](O)(CC[C@@H](C)[C@H]2CC[C@H]3[C@@H]4CC[C@H]5C[C@@](O)(CC[C@]5(C)[C@H]4CC[C@]23C)C(F)(F)F)CC1

InChI Key InChIKey=MGJRHNCCGCXLDO-BDWOQMJISA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521609   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Sage Therapeutics

US Patent
LigandPNGBDBM521609(US11149054, Compound 4657)
Affinity DataEC50:  130nMAssay Description:The whole-cell patch-clamp technique was used to investigate the effects of positive allosteric modulating activity of test compounds on GlunN1/GluN2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Sage Therapeutics

US Patent
LigandPNGBDBM521609(US11149054, Compound 4657)
Affinity DataEC50:  422nMAssay Description:The whole-cell patch-clamp technique was used to investigate the effects of positive allosteric modulating activity of test compounds on GlunN1/GluN2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent