BDBM521748 US11149067, Compound Ahp7

SMILES CC(C)C[C@@H]1N2[C@H](O)CC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)C(C)NC(=O)OCc3ccccc3)[C@@H](C)OC(=O)[C@@H](NC(=O)[C@H](C)N(C)C1=O)C(C)C)C(C)C)C2=O

InChI Key InChIKey=NTESMUWTZGMXHC-RAHQUKOBSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 521748   

TargetNeutrophil elastase(Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521748(US11149067, Compound Ahp7)
Affinity DataKi:  110nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA2, mitochondrial(Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521748(US11149067, Compound Ahp7)
Affinity DataKi:  6.90E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521748(US11149067, Compound Ahp7)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA3 [111-436](Human)
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521748(US11149067, Compound Ahp7)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChymotrypsinogen B(Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521748(US11149067, Compound Ahp7)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease 1(Bos taurus (bovine))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521748(US11149067, Compound Ahp7)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent