BDBM522037 N-[3-[6-(difluoromethoxy)- 3,4-dihydro-2H-1,4- benzothiazin-7-yl]-1-[(1- methyltetrazol-5- yl)methyl]pyrazol-4- yl]pyrazolo[1,5-a]pyrimidine- 3-carboxamide::US11155557, Example 127

SMILES Cn1nnnc1Cn1cc(NC(=O)c2cnn3cccnc23)c(n1)-c1cc2SCCNc2cc1OC(F)F

InChI Key InChIKey=DUNMNNOSTARHFC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522037   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM522037(N-[3-[6-(difluoromethoxy)- 3,4-dihydro-2H-1,4- ben...)
Affinity DataKi:  0.0600nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM522037(N-[3-[6-(difluoromethoxy)- 3,4-dihydro-2H-1,4- ben...)
Affinity DataKi:  0.120nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent