BDBM522959 1-(4-(4-amino-7- cyclopropyl-7H- pyrrolo[2,3- d]pyrimidin-5-yl)-2- fluorophenyl)-3-(5- cyclopropylisoxazol-3- yl)urea::US11161852, Compound 6::US11713321, Example 6

SMILES Nc1ncnc2n(cc(-c3ccc(NC(=O)Nc4cc(on4)C4CC4)c(F)c3)c12)C1CC1

InChI Key InChIKey=OAWSWXJQBVWYLB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522959   

TargetSerine/threonine-protein kinase Nek7(Homo sapiens (Human))
Halia Therapeutics

US Patent
LigandPNGBDBM522959(1-(4-(4-amino-7- cyclopropyl-7H- pyrrolo[2,3- d]py...)
Affinity DataIC50:  400nMAssay Description:Casein substrate (from bovine milk, hydrolyzed and partially dephosphorylated mixture of α, β and κ caseins, obtained from Sigma Aldri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Nek7(Homo sapiens (Human))
Halia Therapeutics

US Patent
LigandPNGBDBM522959(1-(4-(4-amino-7- cyclopropyl-7H- pyrrolo[2,3- d]py...)
Affinity DataIC50:  400nMAssay Description:Casein substrate (from bovine milk, hydrolyzed and partially dephosphorylated mixture of α, β and a caseins, obtained from Sigma Aldrich, c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent