BDBM524064 US11136336, Example 15

SMILES O[C@@H](Cc1noc(Cn2cnc3sc4c(CCNC4=O)c3c2=O)n1)c1ccc(Cl)cc1

InChI Key InChIKey=AGKMZNQCTOWDFF-ZDUSSCGKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 524064   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM524064(US11136336, Example 15)
Affinity DataIC50:  9nMAssay Description:Antagonist activity against human TRPA1 expressed in HEK293K cells assessed as inhibition of AITC-induced intracellular calcium accumulation measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM524064(US11136336, Example 15)
Affinity DataIC50:  9nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat.R8191 Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent