BDBM526962 5-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- yl)-N-(4-fluorophenyl)-2-methylbenzamide::US11186579, Example 27

SMILES Cc1ccc(cc1C(=O)Nc1ccc(F)cc1)-c1cccn2c(cnc12)-c1cccc(F)c1F

InChI Key InChIKey=INDRIIAXOWAOLF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 526962   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526962(5-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  45nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent