BDBM526963 5-(3-(2,3-difluorophenyl)-2- (hydroxymethyl)imidazo[1,2-a]pyridin-8-yl)-N- (4-fluorophenyl)-2-(trifluoromethyl)benzamide::US11186579, Example 28

SMILES OCc1nc2c(cccn2c1-c1cccc(F)c1F)-c1ccc(c(c1)C(=O)Nc1ccc(F)cc1)C(F)(F)F

InChI Key InChIKey=QRKAMKDNHYRZQV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 526963   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526963(5-(3-(2,3-difluorophenyl)-2- (hydroxymethyl)imidaz...)
Affinity DataEC50:  40nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent