BDBM526965 5-(3-(2,3-difluorophenyl)imidazo[1,2- b]pyridazin-8-yl)-N-(4-fluorophenyl)-2- (trifluoromethyl)benzamide::US11186579, Example 30

SMILES Fc1ccc(NC(=O)c2cc(ccc2C(F)(F)F)-c2ccnn3c(cnc23)-c2cccc(F)c2F)cc1

InChI Key InChIKey=IXOJUYFIKSBUHU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 526965   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM526965(5-(3-(2,3-difluorophenyl)imidazo[1,2- b]pyridazin-...)
Affinity DataEC50:  25nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent