BDBM527541 4-(1-(2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethyl)-5-methyl-6-(oxazol-2-yl)-2, 4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)benzoic Acid::US11186587, Example 24

SMILES COc1ccccc1C(Cn1c2sc(c(C)c2c(=O)n(-c2ccc(cc2)C(O)=O)c1=O)-c1ncco1)OC1CCOCC1

InChI Key InChIKey=ZZVHZBGMDIDEER-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 527541   

TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Nanjing Sanhome Pharmaceutical

US Patent
LigandPNGBDBM527541(4-(1-(2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-...)
Affinity DataIC50:  5.12nMAssay Description:4.5 μL of 2.2×ACC2 enzyme (1.1 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Nanjing Sanhome Pharmaceutical

US Patent
LigandPNGBDBM527541(4-(1-(2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-...)
Affinity DataIC50:  3.06nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent