BDBM527884 (3S,4S)-3- methyl-8-(8-((2- (methylthio)phenyl) thio)imidazo[1,2-c] pyrimidin-5- yl)-2-oxa-8- azaspiro[4.5] decan-4-amine::US11179397, Example 101
SMILES CSc1ccccc1Sc1cnc(N2CCC3(CO[C@@H](C)[C@H]3N)CC2)n2ccnc12
InChI Key InChIKey=BXTWXMGCORYKBG-HNAYVOBHSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 527884
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 5.70nMAssay Description:Inhibition of SHP-2 activity by small molecule inhibitors was monitored by a biochemical DiFMUP pseudosubstrate-fluorogenic assay. SHP-2 enzyme at fi...More data for this Ligand-Target Pair