BDBM527923 (S)-1'-(8-((2- (ethylthio)phenyl) thio)imidazo[1,2-c] pyrimidin-5- yl)-1,3- dihydrospiro [indene-2,4'- piperidin]-1- amine::US11179397, Example 142
SMILES CCSc1ccccc1Sc1cnc(N2CCC3(Cc4ccccc4[C@H]3N)CC2)n2ccnc12
InChI Key InChIKey=UQWFEWOXHJBXTG-XMMPIXPASA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 527923
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP-2 activity by small molecule inhibitors was monitored by a biochemical DiFMUP pseudosubstrate-fluorogenic assay. SHP-2 enzyme at fi...More data for this Ligand-Target Pair