BDBM530924 6-(azetidin-3-ylsulfonyl)-3-[4- (2-hydroxyethyl)piperidin-1- yl]-2-(1H-tetrazol-5- yl)benzenesulfonamide::US11207312, Example 56

SMILES NS(=O)(=O)c1c(ccc(N2CCC(CCO)CC2)c1-c1nnn[nH]1)S(=O)(=O)C1CNC1

InChI Key InChIKey=MWJSNGDGUXWXJE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 530924   

TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM530924(6-(azetidin-3-ylsulfonyl)-3-[4- (2-hydroxyethyl)pi...)
Affinity DataIC50:  0.760nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM530924(6-(azetidin-3-ylsulfonyl)-3-[4- (2-hydroxyethyl)pi...)
Affinity DataIC50:  0.820nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM530924(6-(azetidin-3-ylsulfonyl)-3-[4- (2-hydroxyethyl)pi...)
Affinity DataIC50:  0.25nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM530924(6-(azetidin-3-ylsulfonyl)-3-[4- (2-hydroxyethyl)pi...)
Affinity DataIC50:  0.450nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent