BDBM531020 (R)-4-(3-(hydroxyimino)-2-oxopiperidin-1-yl)-N1-(pyrrolidin-3-yl)-3-(2H-tetrazol-5-yl)benzene-1,2-disulfonamide::US11207312, Example 152

SMILES NS(=O)(=O)c1c(ccc(N2CCC\C(=N\O)C2=O)c1[N]1=NNN=N1)S(=O)(=O)N[C@@H]1CCNC1

InChI Key InChIKey=IXFMLUGXQNACQX-HXOGEXJKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 531020   

TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM531020((R)-4-(3-(hydroxyimino)-2-oxopiperidin-1-yl)-N1-(p...)
Affinity DataIC50:  0.0800nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM531020((R)-4-(3-(hydroxyimino)-2-oxopiperidin-1-yl)-N1-(p...)
Affinity DataIC50:  0.740nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM531020((R)-4-(3-(hydroxyimino)-2-oxopiperidin-1-yl)-N1-(p...)
Affinity DataIC50:  0.160nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM531020((R)-4-(3-(hydroxyimino)-2-oxopiperidin-1-yl)-N1-(p...)
Affinity DataIC50:  6.80nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent