BDBM540739 US11261211, Compound SA-8

SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@H]34)[C@@H]1CC[C@@H]2C(=O)Cn1ncc2CCCCc12

InChI Key InChIKey=QYEIQYJLVREYBI-MOYGJMECSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 540739   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Sage Therapeutics

US Patent
LigandPNGBDBM540739(US11261211, Compound SA-8)
Affinity DataEC50:  1.50E+3nMAssay Description:This assay is not specified.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Sage Therapeutics

US Patent
LigandPNGBDBM540739(US11261211, Compound SA-8)
Affinity DataIC50:  30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent