BDBM544834 US11286268, Compound 318

SMILES Cc1c(c2cc(cc(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(csc12)C(O)=O)C(F)(F)F)S(C)(=O)=O

InChI Key InChIKey=AVOYSCOGURUPLS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 544834   

TargetEukaryotic translation initiation factor 4E-binding protein 1(Homo sapiens (Human))
Effector Therapeutics

US Patent
LigandPNGBDBM544834(US11286268, Compound 318)
Affinity DataIC50:  2.92nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent