BDBM547730 US11292792, CMPD # I-60

SMILES CC(C)(C)OC(=O)NCCOCCOCCCc1cccc2n(C3CCC(=O)NC3=O)c3ncccc3c12

InChI Key InChIKey=WAYCCNFZQDZGBS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 547730   

TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
Kymera Therapeutics

US Patent
LigandPNGBDBM547730(US11292792, CMPD # I-60)
Affinity DataIC50: <10nMAssay Description:Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent