BDBM549075 BDBM50556877::US11299480, Example 34
SMILES OC(=O)c1ccc(cc1O)N(Cc1ccc(cc1)C1CCCCC1)C(=O)[C@H]1CCN1S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F
InChI Key InChIKey=AJNPQBGORGGVKZ-OAQYLSRUSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 549075
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Hawaii Cancer Center
Curated by ChEMBL
University Of Hawaii Cancer Center
Curated by ChEMBL
Affinity DataIC50: 520nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Hawaii
US Patent
University of Hawaii
US Patent
Affinity DataIC50: 546nMAssay Description:Nuclear extract preparations and DNA-binding activity/electrophoretic mobility shift assay (EMSA) were carried out as previously described (Zhang X, ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1(Mus musculus)
University Of Hawaii Cancer Center
Curated by ChEMBL
University Of Hawaii Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT1 homodimer in mouse NIH3T3 nuclear extract preincubate...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1/3(Mus musculus (mouse))
University Of Hawaii Cancer Center
Curated by ChEMBL
University Of Hawaii Cancer Center
Curated by ChEMBL
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT1/STAT3 heterodimer in mouse NIH3T3 nuclear extract pre...More data for this Ligand-Target Pair