BDBM549310 BDBM50556881::US11299480, Example 64

SMILES OC(=O)c1cc(F)c(cc1O)N(Cc1ccc(cc1)C1CCOCC1)C(=O)[C@H]1CCN1S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F

InChI Key InChIKey=KOKRGBJLKIGARP-LJQANCHMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 549310   

TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Hawaii

US Patent
LigandPNGBDBM549310(BDBM50556881 | US11299480, Example 64)
Affinity DataIC50:  809nMAssay Description:Nuclear extract preparations and DNA-binding activity/electrophoretic mobility shift assay (EMSA) were carried out as previously described (Zhang X, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Hawaii Cancer Center

Curated by ChEMBL
LigandPNGBDBM549310(BDBM50556881 | US11299480, Example 64)
Affinity DataIC50:  810nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed