BDBM552600 3-(3-chloro-2-methoxyanilino)-2-(3-{[(2S)-1-(prop-2-enoyl)pyrrolidin-2-yl]methoxy}pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one::WO2022101184, Example 13
SMILES COc1c(Cl)cccc1Nc1c([nH]c2CCNC(=O)c12)-c1ccncc1OC[C@@H]1CCCN1C(=O)C=C
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 552600
TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Homo sapiens (Human))
Bayer Aktiengesellschaft
WIPO
Bayer Aktiengesellschaft
WIPO
Affinity DataIC50: 0.210nMAssay Description: Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se...More data for this Ligand-Target Pair