BDBM552600 3-(3-chloro-2-methoxyanilino)-2-(3-{[(2S)-1-(prop-2-enoyl)pyrrolidin-2-yl]methoxy}pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one::WO2022101184, Example 13

SMILES COc1c(Cl)cccc1Nc1c([nH]c2CCNC(=O)c12)-c1ccncc1OC[C@@H]1CCCN1C(=O)C=C

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552600   

TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Homo sapiens (Human))
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WIPO
LigandPNGBDBM552600(3-(3-chloro-2-methoxyanilino)-2-(3-{[(2S)-1-(prop-...)
Affinity DataIC50:  0.210nMAssay Description: Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed