BDBM552801 (R)-7-(3-(2-(5-(Methylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)thiazol-4-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-7-ol.::WO2022104348, Example 28

SMILES CS(=O)(=O)c1cnc2[nH]cc(-c3nc(cs3)-c3cccc(c3)[C@]3(O)Cc4nccn4C3)c2c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552801   

TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552801((R)-7-(3-(2-(5-(Methylsulfonyl)-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50: <100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreenŽ (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed