BDBM555114 3-[(3-fluorophenyl)amino]-2-(3-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one::US11339157, Example 8

SMILES CN1CCC[C@H]1COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 555114   

TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Homo sapiens (Human))
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US Patent
LigandPNGBDBM555114(3-[(3-fluorophenyl)amino]-2-(3-{[(2S)-1-methylpyrr...)
Affinity DataIC50:  0.310nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent