BDBM558 N-{3-[(1R)-1-[(6R)-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-5,6-dihydro-2H-pyran-3-yl]propyl]phenyl}-5-(trifluoromethyl)pyridine-2-sulfonamide::PNU-140690::Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones::Tipranavir::U-140690
SMILES CCC[C@@]1(CCc2ccccc2)CC(=O)C([C@H](CC)c2cccc(NS(=O)(=O)c3ccc(cn3)C(F)(F)F)c2)C(=O)O1
InChI Key InChIKey=MYXACKZCYFKMTE-JETRDCLMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 558
Affinity DataKi: 0.00800nM ΔG°: -15.0kcal/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of mouse ZMPSTE24 expressed n delta ste24 delta rce1 yeastMore data for this Ligand-Target Pair