BDBM558309 2,2-Dimethyl-5-[3-[[6-(1H-pyrazol-5-yl)-3-pyridinyl]oxymethyl]phenyl] sulfonylpentanoic Acid::US11365192, Example 37-1

SMILES CC(C)(CCCS(=O)(=O)c1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1)C(O)=O

InChI Key InChIKey=JNDHYNIQOJQCTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 558309   

TargetCytochrome P450 4A11(Homo sapiens)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558309(2,2-Dimethyl-5-[3-[[6-(1H-pyrazol-5-yl)-3-pyridiny...)
Affinity DataIC50:  46nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 4F2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558309(2,2-Dimethyl-5-[3-[[6-(1H-pyrazol-5-yl)-3-pyridiny...)
Affinity DataIC50:  32nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent