BDBM565350 US11414416, Compound D117::US11560381, Compound D117
SMILES COc1cc(cc(OC)c1CN1CC(CCNC(=O)CCOCCOc2ccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c3c2)C1)-c1cn(C)c(=O)c2cnccc12
InChI Key InChIKey=BHUXHSLFYQQICS-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 565350
Affinity DataIC50: <10nMAssay Description:Procedure: His-Flag-BRD9 (P133-K239; Swiss Prot Q9H8M2; SEQ ID NO:1 mgsshhhhhhenlyfq/gdykddddkgslevlfqg/PAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMII...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:A mixture of biotinylated-ligand and SureLight Allophycocyanin-Streptavidin (APC-SA, PerkinElmer AD0201) in 50 mM HEPES (pH 7.4), 50 mM NaCl, 1 mM TC...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair