BDBM575988 US11466016, Example 122::{3- [(1R,2S,3S,5S)-3- amino-2-fluoro-8- azabicyclo[3.2.1]oc- tan-8-yl]-7-(3,4- dichloro-2-methyl- 2H-indazol-5-yl)- 5H-pyrrolo[2,3- b]pyrazin-2- yl}methanol

SMILES Cn1nc2ccc(-c3c[nH]c4nc(N5[C@H]6CC[C@@H]5[C@@H](F)[C@@H](N)C6)c(CO)nc34)c(Cl)c2c1Cl

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575988   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM575988(US11466016, Example 122 | {3- [(1R,2S,3S,5S)-3- am...)
Affinity DataIC50:  5.20nMAssay Description:SHP2 activity was monitored by measuring the conversion of the surrogate substrate 6,8-difluoromethylumbelliferyl phosphate (DiFMUP) to the fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent