BDBM575997 US11466016, Example 131::{6-[endo-3-amino-3- methyl-8- azabicyclo[3.2.1] octan-8-yl]- 3-[5-chloro-3- (dimethylamino) quinoxalin- 6-yl]-1H- pyrazolo[3,4- b]pyrazin-5- yl}methanol

SMILES CN(C)c1cnc2ccc(-c3n[nH]c4nc(N5[C@H]6CC[C@@H]5C[C@@](C)(N)C6)c(CO)nc34)c(Cl)c2n1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575997   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM575997(US11466016, Example 131 | {6-[endo-3-amino-3- met...)
Affinity DataIC50:  8.80nMAssay Description:SHP2 activity was monitored by measuring the conversion of the surrogate substrate 6,8-difluoromethylumbelliferyl phosphate (DiFMUP) to the fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent