BDBM585798 US11530229, Compound 13

SMILES CC1CCCN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)[C@@]2(Cc3nncn3C)C[C@@H](C2)C#N)CC1

InChI Key InChIKey=WRWBXQMNSPBQNV-AVCJDWODSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585798   

TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585798(US11530229, Compound 13)
Affinity DataIC50:  3.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent