BDBM585799 US11530229, Compound 14

SMILES Cn1cnnc1C[C@@]1(C[C@@H](C1)C#N)c1cccc(c1)N1Cc2c(cc(CN3CCC[C@@H](C3)C(F)(F)F)cc2C(F)(F)F)C1=O

InChI Key InChIKey=YGLPIRUNHRZFLN-GOGYHYQUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585799   

TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585799(US11530229, Compound 14)
Affinity DataIC50:  3.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent