BDBM588182 US11542251, Compound TL2

SMILES C=CC(=O)Nc1cccc(c1)C(=O)Nc1ccc(NC(=O)c2cccc(c2)-c2ccn[nH]2)cc1

InChI Key InChIKey=JECFXYJOFJETGU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588182   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588182(US11542251, Compound TL2)
Affinity DataIC50: >1.00E+4nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta® kinase assay format, and a Z′-LYTE™ kinases a...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588182(US11542251, Compound TL2)
Affinity DataIC50:  9nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta® kinase assay format, and a Z′-LYTE™ kinases a...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent