BDBM593712 US11578080, Example 18

SMILES O[C@@H](Cn1nnc(Cn2cnc3sc4c(CCNC4=O)c3c2=O)n1)c1cc2cc(Cl)ccc2o1

InChI Key InChIKey=ROWLJZVZKLFWIP-ZDUSSCGKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593712   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM593712(US11578080, Example 18)
Affinity DataIC50:  14nMAssay Description:At the assay day cells were washed 3× with assay puffer, 20 μL buffer remained in the wells after washing. 10 μL Ca6 kit (Cat. R8191 Molecu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent