BDBM603012 2-amino-N-(3-(5-chloro-2- (difluoromethoxy)phenyl)-1H- pyrazol-4-yl)thiazolo[5,4-c]pyridine- 7-carboxamide::US11649241, Example 5

SMILES Nc1nc2c(cncc2s1)C(=O)Nc1c[nH]nc1-c1cc(Cl)ccc1OC(F)F

InChI Key InChIKey=ROUUBNNTZMLFCL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 603012   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM603012(2-amino-N-(3-(5-chloro-2- (difluoromethoxy)phenyl)...)
Affinity DataKi:  0.0600nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM603012(2-amino-N-(3-(5-chloro-2- (difluoromethoxy)phenyl)...)
Affinity DataKi:  0.970nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent