BDBM605115 (2S,5S)-5-{(2S,3S)-2-[2-(2-Fluoro- ethoxy)-acetylamino]-3-methyl- pentanoylamino}-4-oxo-1,2,4,5,6,7- hexahydro-azepino[3,2,1-hi]indole-2- carboxylic acid (1H-[1,2,3]-triazol-4- ylmethyl)-amide::US11667645, Compound C058::US11667645, Compound C145

SMILES CC[C@H](C)[C@H](NC(=O)COCCF)C(=O)N[C@H]1CCc2cccc3C[C@H](N(c23)C1=O)C(=O)NCc1c[nH]nn1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 605115   

TargetGranzyme B(Homo sapiens (Human))
Cytosite Biopharma

US Patent
LigandPNGBDBM605115((2S,5S)-5-{(2S,3S)-2-[2-(2-Fluoro- ethoxy)-acetyla...)
Affinity DataIC50:  150nMAssay Description:Buffer pH7.4: Prepare 1 (M) KH2PO4 and 1 (M) K2HPO4. Titrate 1(M) K2HPO4 with 1 (M) KH2PO4 to obtain pH 7.40. Dilute this buffer 10 fold in Water (30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGranzyme B(Homo sapiens (Human))
Cytosite Biopharma

US Patent
LigandPNGBDBM605115((2S,5S)-5-{(2S,3S)-2-[2-(2-Fluoro- ethoxy)-acetyla...)
Affinity DataIC50:  150nMAssay Description:Buffer pH7.4: Prepare 1 (M) KH2PO4 and 1 (M) K2HPO4. Titrate 1(M) K2HPO4 with 1 (M) KH2PO4 to obtain pH 7.40. Dilute this buffer 10 fold in Water (30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent