BDBM60862 BDBM189328::US9174940, 32

SMILES CC(=O)N1CCC(C)(C2C=C(NC(=O)OC3CCCC3)C=CC12)c1ccccc1

InChI Key InChIKey=BYYWYRYHYCVCLI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 60862   

TargetThyrotropin receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60862(BDBM189328 | US9174940, 32)
Affinity DataIC50: <100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThyrotropin receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60862(BDBM189328 | US9174940, 32)
Affinity DataIC50:  12nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThyrotropin subunit beta(Bos taurus (Bovine))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60862(BDBM189328 | US9174940, 32)
Affinity DataIC50:  48nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent