BDBM610449 2-(3-Cyclopropyl-pyrazol-1-yl)-1-{(S)-2-hydroxymethyl-4-[2-trifluoromethyl-4-(2-trifluoromethyl-pyrimidin-5-yl)-thiazol-5-yl]-piperazin-1-yl}-ethanone::US10053457, Example 44
SMILES OC[C@@H]1CN(CCN1C(=O)Cn1ccc(n1)C1CC1)c1sc(nc1-c1cnc(nc1)C(F)(F)F)C(F)(F)F
InChI Key InChIKey=XLDNJQXRMYVGDR-AWEZNQCLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 610449
Affinity DataIC50: 76nMAssay Description:Stock solutions of test compounds are made up at a concentration of 10 mM in DMSO, and serially diluted in PBS containing 0.5% BSA to concentrations ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair