BDBM614748 3-Chloro-2-[6- (1,1- difluoropropyl) pyridin-3-yl]-5- [({1-[2-fluoro-4- (trifluoromethoxy) phenyl]cyclo- propyl}carbonyl) amino]benzoic acid::US20230271931, Example 106

SMILES CCC(F)(F)c1ccc(cn1)-c1c(Cl)cc(NC(=O)C2(CC2)c2ccc(OC(F)(F)F)cc2F)cc1C(O)=O

InChI Key InChIKey=NOTXFEUYPGEODC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614748   

TargetB1 bradykinin receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614748(3-Chloro-2-[6- (1,1- difluoropropyl) pyridin-3-yl]...)
Affinity DataIC50:  35nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the presence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetB1 bradykinin receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM614748(3-Chloro-2-[6- (1,1- difluoropropyl) pyridin-3-yl]...)
Affinity DataIC50:  8.40nMAssay Description:Notably, Compound Examples are tested in the FLIPR assays in the absence (hB1 free IC50) of 0.1% BSA in assay buffer, in order to assess the potency ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent