BDBM6164 1,6-naphthyridine 33::1-[3-(2,6-dichlorophenyl)-7-{[3-(4-methylpiperazin-1-yl)propyl]amino}-1,6-naphthyridin-2-yl]-3-ethylurea::N-[3-(2,6-Dichlorophenyl)-7-[[3-(4-methyl-1-piperazinyl)-propyl]amino]-1,6-naphthyridin-2-yl]-N -ethylurea

SMILES CCNC(=O)Nc1nc2cc(NCCCN3CCN(C)CC3)ncc2cc1-c1c(Cl)cccc1Cl

InChI Key InChIKey=WQZLHIFJXAIOQL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 6164   

TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
University of Auckland

LigandPNGBDBM6164(1,6-naphthyridine 33 | 1-[3-(2,6-dichlorophenyl)-7...)
Affinity DataIC50:  540nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6164(1,6-naphthyridine 33 | 1-[3-(2,6-dichlorophenyl)-7...)
Affinity DataIC50:  110nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6164(1,6-naphthyridine 33 | 1-[3-(2,6-dichlorophenyl)-7...)
Affinity DataIC50:  19nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6164(1,6-naphthyridine 33 | 1-[3-(2,6-dichlorophenyl)-7...)
Affinity DataIC50:  32nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed