BDBM6200 Benzofuran deriv. 9::N-(5-Chloro-1-benzofuran-4-yl)-6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-amine Dihydrochloride::N-(5-chloro-1-benzofuran-4-yl)-6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine dihydrochloride

SMILES COc1cc2c(Nc3c(Cl)ccc4occc34)ncnc2cc1OCCCN1CCOCC1

InChI Key InChIKey=DYYRSMHBLLWJOD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6200   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6200(Benzofuran deriv. 9 | N-(5-Chloro-1-benzofuran-4-y...)
Affinity DataIC50:  1.23E+3nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM6200(Benzofuran deriv. 9 | N-(5-Chloro-1-benzofuran-4-y...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed