BDBM621246 US11771711, Example 2

SMILES CCc1c(C#N)c(S[C@@H](C(N)=O)c2ccc(OS(C)(=O)=O)cc2)nc(N(C)C)c1C#N

InChI Key InChIKey=LCRRAHSMOCDGGH-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621246   

TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM621246(US11771711, Example 2)
Affinity DataIC50:  54nMAssay Description:This assay used Scintillation Proximity technology in a signal increase format to evaluate the potency of compounds. Full-length human DNMT1, hemi-me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent