BDBM626317 2-[[[7-(4-isopropylphenyl)-2,3- dihydrobenzofuran-5- yl]amino]methyl]prop-2-enamide::US11787775, Compound 2
SMILES CC(C)c1ccc(cc1)-c1cc(NCC(=C)C(N)=O)cc2CCOc12
InChI Key InChIKey=HVUUZUONXZOUQH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 626317
Affinity DataIC50: 590nMAssay Description:Table 2-3: His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid p...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Table 2-3: His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Table 2-3: His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid p...More data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-3/Isoform 5 of Transcriptional coactivator [50-100](Homo sapiens)
Genentech
US Patent
Genentech
US Patent
Affinity DataEC50: 90nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-1/Isoform 5 of Transcriptional coactivator [50-100](Homo sapiens)
Genentech
US Patent
Genentech
US Patent
Affinity DataEC50: 460nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-4/Isoform 5 of Transcriptional coactivator [50-100](Homo sapiens)
Genentech
US Patent
Genentech
US Patent
Affinity DataEC50: 70nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-5/Isoform 5 of Transcriptional coactivator [50-100](Homo sapiens)
Genentech
US Patent
Genentech
US Patent
Affinity DataEC50: 1.80E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Table 2-3: His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid p...More data for this Ligand-Target Pair