BDBM628565 US20230339882, Example A09

SMILES COc1ccc(OCC#Cc2cnc(N3CCC4(Cc5ccccc5[C@H]4N)CC3)c(CO)n2)cc1

InChI Key InChIKey=KIJXVNSDLGUUMB-AREMUKBSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 628565   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM628565(US20230339882, Example A09)
Affinity DataIC50:  0.900nMAssay Description:SHP2 is allosterically activated by binding of a bis-tyrosyl-phosphorylated peptide to its Src homology 2 (SH2) domain. This later activation step re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent