BDBM628565 US20230339882, Example A09
SMILES COc1ccc(OCC#Cc2cnc(N3CCC4(Cc5ccccc5[C@H]4N)CC3)c(CO)n2)cc1
InChI Key InChIKey=KIJXVNSDLGUUMB-AREMUKBSSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 628565
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Betta Pharmaceuticals
US Patent
Betta Pharmaceuticals
US Patent
Affinity DataIC50: 0.900nMAssay Description:SHP2 is allosterically activated by binding of a bis-tyrosyl-phosphorylated peptide to its Src homology 2 (SH2) domain. This later activation step re...More data for this Ligand-Target Pair