BDBM635771 US20230365488, Compound 2b

SMILES OC(=O)C1[C@@H]([C@@H]([C@H]1c1ccccc1)C(=O)Oc1cc(ccc1C#N)-c1ccccc1)c1ccccc1

InChI Key InChIKey=YHECONUSIINGSG-CVRJERCRSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 635771   

TargetFatty acid-binding protein 5(Homo sapiens (Human))
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM635771(US20230365488, Compound 2b)
Affinity DataKi:  330nMAssay Description:Purified FABPs (3 μM) were incubated with fluorescent probe (500 nM) in 30 mM Tris, 100 mM NaCl buffer (pH 7.5). Compounds to be tested were the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid-binding protein, brain(Homo sapiens)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM635771(US20230365488, Compound 2b)
Affinity DataKi:  460nMAssay Description:Purified FABPs (3 μM) were incubated with fluorescent probe (500 nM) in 30 mM Tris, 100 mM NaCl buffer (pH 7.5). Compounds to be tested were the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFABP3 protein(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM635771(US20230365488, Compound 2b)
Affinity DataKi:  720nMAssay Description:Purified FABPs (3 μM) were incubated with fluorescent probe (500 nM) in 30 mM Tris, 100 mM NaCl buffer (pH 7.5). Compounds to be tested were the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent