BDBM635903 (1R,2S)-2-(3-{[(3S)-3-hydroxy-2,3-dihydro-1-benzofuran-7-yl]amino}-1H-indazol-6-yl)-5'-methoxyspiro[cyclopropane-1,3'-indol]-2'(1'H)-one::US20230365537, Example 28

SMILES COc1ccc2NC(=O)[C@@]3(C[C@H]3c3ccc4c(Nc5cccc6[C@H](O)COc56)n[nH]c4c3)c2c1

InChI Key InChIKey=DBZHXGIFTZJKCP-MNDLBQGCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 635903   

TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635903((1R,2S)-2-(3-{[(3S)-3-hydroxy-2,3-dihydro-1-benzof...)
Affinity DataIC50:  0.375nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent