BDBM637523 US20230382911, Example 35::[3-amino-6-(2,5-dihydrofuran-3- yl)pyrazolo[3,4-b]pyridin-1-yl]- (2-methoxyphenyl)methanone

SMILES COc1ccccc1C(=O)n1nc(N)c2ccc(nc12)C1=CCOC1

InChI Key InChIKey=ALTMKGNEJAZAAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 637523   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM637523(US20230382911, Example 35 | [3-amino-6-(2,5-dihydr...)
Affinity DataIC50:  17nMAssay Description:Recombinant human Mat2a (12.5 nM) and serial diluted compounds in DMSO (range of concentrations from 10 μM to 508 μM) or controls (DMSO) ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent