BDBM637564 (3-amino-6-cyclopropyl-1H- pyrazolo[3,4-b]pyridin-1-yl)(2- chloropyridin-3-yl)methanone::US20230382911, Example 76

SMILES Nc1nn(C(=O)c2cccnc2Cl)c2nc(ccc12)C1CC1

InChI Key InChIKey=JGGDUJKLNJRSIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 637564   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM637564((3-amino-6-cyclopropyl-1H- pyrazolo[3,4-b]pyridin-...)
Affinity DataIC50:  17nMAssay Description:Recombinant human Mat2a (12.5 nM) and serial diluted compounds in DMSO (range of concentrations from 10 μM to 508 μM) or controls (DMSO) ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent