BDBM639321 Methyl 3-{[(5-chloro-2-thienyl)carbonyl]amino}-N-{[2-methyl-3-(2-oxopyrrolidin-1-yl)phenyl]-sulfonyl}-S-alaninate::US20230391761, Reference 4

SMILES COC(=O)[C@H](CNC(=O)c1ccc(Cl)s1)NS(=O)(=O)c1cccc(N2CCCC2=O)c1C

InChI Key InChIKey=JLNIRPLGKIIBBC-ZDUSSCGKSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 639321   

TargetCoagulation factor X(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM639321(Methyl 3-{[(5-chloro-2-thienyl)carbonyl]amino}-N-{...)
Affinity DataIC50:  0.490nMAssay Description:Determination of the Selectivity To demonstrate the selectivity of the substances with respect to thrombin and factor Xa inhibition, the test substan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM639321(Methyl 3-{[(5-chloro-2-thienyl)carbonyl]amino}-N-{...)
Affinity DataIC50:  26nMAssay Description:Determination of the Selectivity To demonstrate the selectivity of the substances with respect to thrombin and factor Xa inhibition, the test substan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM639321(Methyl 3-{[(5-chloro-2-thienyl)carbonyl]amino}-N-{...)
Affinity DataIC50: >5.00E+4nMAssay Description:Determination of the Selectivity To demonstrate the selectivity of the substances with respect to thrombin and factor Xa inhibition, the test substan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKallikrein-1(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM639321(Methyl 3-{[(5-chloro-2-thienyl)carbonyl]amino}-N-{...)
Affinity DataIC50:  5.70E+3nMAssay Description:Determination of the Selectivity To demonstrate the selectivity of the substances with respect to thrombin and factor Xa inhibition, the test substan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasminogen(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM639321(Methyl 3-{[(5-chloro-2-thienyl)carbonyl]amino}-N-{...)
Affinity DataIC50: >5.00E+4nMAssay Description:Determination of the Selectivity To demonstrate the selectivity of the substances with respect to thrombin and factor Xa inhibition, the test substan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM639321(Methyl 3-{[(5-chloro-2-thienyl)carbonyl]amino}-N-{...)
Affinity DataIC50:  1.20E+3nMAssay Description:Determination of the Selectivity To demonstrate the selectivity of the substances with respect to thrombin and factor Xa inhibition, the test substan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM639321(Methyl 3-{[(5-chloro-2-thienyl)carbonyl]amino}-N-{...)
Affinity DataIC50:  4.10E+4nMAssay Description:Determination of the Selectivity To demonstrate the selectivity of the substances with respect to thrombin and factor Xa inhibition, the test substan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent