BDBM640774 US20230399319, Example 2-336

SMILES CC(C)c1cc(Nc2nc(co2)C(=O)NS(=O)(=O)N2CCCOCC2)c(C)cc1F

InChI Key InChIKey=IXEYPSGSJHBINH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640774   

TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Japan Tobacco

US Patent
LigandPNGBDBM640774(US20230399319, Example 2-336)
Affinity DataIC50:  10nMAssay Description:The NLRP3 inflammasome inhibitory activity of test compounds were evaluated CM the basis of the inhibitory activity of the IL-1β, production in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent