BDBM640780 US20230399319, Example 2-342

SMILES Cc1ccc(C)c(Nc2nc(co2)C(=O)NS(=O)(=O)N2CCOC(COCC3CCC3)CC2)c1

InChI Key InChIKey=QYNRUGCODMBQNY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640780   

TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Japan Tobacco

US Patent
LigandPNGBDBM640780(US20230399319, Example 2-342)
Affinity DataIC50:  10nMAssay Description:The NLRP3 inflammasome inhibitory activity of test compounds were evaluated CM the basis of the inhibitory activity of the IL-1β, production in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent