BDBM642776 4-(difluoromethyl)-N-(1-((difluoromethyl)sulfonyl)piperidin-4-yl)-1- isopropyl-1H-[1,2,3]triazolo[4,5-h]quinazolin-8-amine::US20230416271, Compound II.30
SMILES CC(C)n1nnc2c(cc3cnc(NC4CCN(CC4)S(=O)(=O)C(F)F)nc3c12)C(F)F
InChI Key InChIKey=VISMKLIGDLCELE-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 642776
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Chengdu Cynogen Bio-Pharmaceutical Technology
US Patent
Chengdu Cynogen Bio-Pharmaceutical Technology
US Patent
Affinity DataIC50: 0.300nMAssay Description:Assay of Kinase Activity The inhibitory effect of compounds against the kinase CDK4/cyclin D3 was detected by Caliper Mobility Shift Assay method. Th...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Chengdu Cynogen Bio-Pharmaceutical Technology
US Patent
Chengdu Cynogen Bio-Pharmaceutical Technology
US Patent
Affinity DataIC50: 6nMAssay Description:Assay of Kinase Activity The inhibitory effect of compounds against the kinase CDK4/cyclin D3 was detected by Caliper Mobility Shift Assay method. Th...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Chengdu Cynogen Bio-Pharmaceutical Technology
US Patent
Chengdu Cynogen Bio-Pharmaceutical Technology
US Patent
Affinity DataIC50: 3nMAssay Description:Assay of Kinase Activity The inhibitory effect of compounds against the kinase CDK4/cyclin D3 was detected by Caliper Mobility Shift Assay method. Th...More data for this Ligand-Target Pair