BDBM643160 N1-(3,5-Dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)cinnolin-6-yl)ethane-1,2-diamine::US20240002365, Example 1

SMILES COc1cc(OC)cc(c1)N(CCNC(C)C)c1ccc2nnc(cc2c1)-c1cnn(C)c1

InChI Key InChIKey=QGWHVBBKJAQYRM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 643160   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Beta Pharma

US Patent
LigandPNGBDBM643160(N1-(3,5-Dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-met...)
Affinity DataIC50:  7.30nMAssay Description:The reaction procedure was conducted as follows:1) Prepare substrate in freshly prepared Reaction Buffer.2) MnCl2 (2 mM) was added as a co-factor lis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Beta Pharma

US Patent
LigandPNGBDBM643160(N1-(3,5-Dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-met...)
Affinity DataIC50:  4.30nMAssay Description:The reaction procedure was conducted as follows:1) Prepare substrate in freshly prepared Reaction Buffer.2) MnCl2 (2 mM) was added as a co-factor lis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Beta Pharma

US Patent
LigandPNGBDBM643160(N1-(3,5-Dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-met...)
Affinity DataIC50:  9.5nMAssay Description:The reaction procedure was conducted as follows:1) Prepare substrate in freshly prepared Reaction Buffer.2) MnCl2 (2 mM) was added as a co-factor lis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Beta Pharma

US Patent
LigandPNGBDBM643160(N1-(3,5-Dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-met...)
Affinity DataIC50:  11nMAssay Description:The reaction procedure was conducted as follows:1) Prepare substrate in freshly prepared Reaction Buffer.2) MnCl2 (2 mM) was added as a co-factor lis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Beta Pharma

US Patent
LigandPNGBDBM643160(N1-(3,5-Dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-met...)
Affinity DataIC50:  7.60nMAssay Description:The reaction procedure was conducted as follows:1) Prepare substrate in freshly prepared Reaction Buffer.2) MnCl2 (2 mM) was added as a co-factor lis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent