BDBM645101 US20240010684, Ex. No 78

SMILES CC[C@H](C)[C@H]1NC(=O)[C@@H]2CCCN2C(=O)CCCCNC(=O)[C@H](CC(C)(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@@H]2CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCCCC[C@@H](N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N2

InChI Key InChIKey=VNNPWXVKSOUCAT-NJFCVMLPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645101   

TargetMannan-binding lectin serine protease 2(Homo sapiens)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645101(US20240010684, Ex. No 78)
Affinity DataIC50:  7nMAssay Description:Recombinant human MASP2 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMannan-binding lectin serine protease 1(Homo sapiens)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645101(US20240010684, Ex. No 78)
Affinity DataIC50:  10nMAssay Description:Recombinant human MASP1 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent